4-Aminophenylboronic acid pinacol ester_product_DataBase

Bioactivity	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Invitro	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline 是一种杂环结构单元。它已用于合成基于 3-氨基吲唑的多靶点受体具有抗癌活性的酪氨酸激酶 (RTK) 抑制剂和 roscovitine 衍生物，它们是细胞周期蛋白依赖性激酶 (CDK) 和酪蛋白激酶 1 (CK1) 的双重抑制剂。
Name	4-Aminophenylboronic acid pinacol ester
CAS	214360-73-3
Formula	C12H18BNO2
Molar Mass	219.09
Appearance	Solid
Transport	Room temperature in continental US; may vary elsewhere.
Storage	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reference	[1]. Dai, Y., Hartandi, K., Ji, Z., et al al. Discovery of N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-aminoindazole-based ORALLY ACTIVE MULTITARGED Receptor Tyrosine Kinase Inchibitorj. Chem.50 (7) 1584-1597 (2007). [2]. Paraiso, KHT, HAARBERG, He, Wood, E., ET Al.The HSP9 0 Inhibitor XL888 Overcomes Braf Inchibitor Resistance Mediated Through diverse mechanisms Clin. Cancer Res. 18(9) 2502-2514(2012).

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