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4-(Dodecylamino)phenol

CAS: 25848-37-7 F: C18H31NO W: 277.44

4-(Dodecylamino)phenol (p-DDAP) is ananticancer agent. 4-(Dodecylamino)phenol has anti-tumor activity and can suppress p
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Bioactivity 4-(Dodecylamino)phenol (p-DDAP) is an anticancer agent. 4-(Dodecylamino)phenol has anti-tumor activity and can suppress proliferation, arrest the cell cycle and induce apoptotic cell death. 4-(Dodecylamino)phenol can be used for the research of cancer, such as prostate cancer[1][2].
Invitro 4-(Dodecylamino)phenol (p-DDAP) (0-10 μM; 72 h) induces growth arrest in NB-39-nu cells[1].p-DDAP (0.1, 0.2, 0.4, 10 μM; ) arrestes the cell cycle in the G0/G1 phase in dose-dependent manner[1].p-DDAP (0.2 μM; 48 h) induces apoptotosis without differentiation[1].p-DDAP (0.2, 0.4, 1 μM; 24 h, 72 h) induces apoptotic cell death through bcl-2 down-regulation and caspases activation[1]. Cell Proliferation Assay[1] Cell Line:
Name 4-(Dodecylamino)phenol
CAS 25848-37-7
Formula C18H31NO
Molar Mass 277.44
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.