Bioactivity | 4-(2-Bromoacetyl)benzonitrile (4-Cyanophenacyl bromide) can be used to the synthesis of STA-5312. STA-5312 is a potent and orally active microtubule inhibitor[1][2]. |
CAS | 20099-89-2 |
Formula | C9H6BrNO |
Molar Mass | 224.05 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. Hao Li, et al. Development of a Practical Synthesis of STA-5312, a Novel Indolizine Oxalylamide Microtubule Inhibitor. Org. Process Res. Dev. 2007, 11, 2, 246–250 [2]. Keizo Koya,et al. STA-5312, a novel tubulin inhibitor, demonstrates the anti-cancer activity against chemotherapy-resistant cancers. Cancer Res, Volume 45, 2004. |