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4,6-Dioxoheptanoic acid

CAS: 51568-18-4 F: C7H10O4 W: 158.15

4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
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Bioactivity 4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
Invitro 4,6-Dioxoheptanoic acid (Succinylacetone, SA) is examined with regard to its ability to a) inhibit the second enzyme of the heme pathway, δ-aminolevulinic acid (ALA) dehydratase, b) lower the heme concentration, and c) inhibit cell growth of murine erythroleukemia (MEL) cells in culture[1].
Name 4,6-Dioxoheptanoic acid
CAS 51568-18-4
Formula C7H10O4
Molar Mass 158.15
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month