| Bioactivity | 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine (Compound 7) is an inhibitor of protein kinases, with IC50s of 0.092, 0.26, 0.77 μM for PKC-α, ROCK, ASK1. 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine shows potent cytotoxicity against PC-3 cancer cells with an IC50 value of 0.16 μM[1]. |
| Name | 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine |
| CAS | 2226941-29-1 |
| Formula | C28H24N4O4 |
| Molar Mass | 480.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang JN, et al. Bioactive Indolocarbazoles from the Marine-Derived Streptomyces sp. DT-A61. J Nat Prod. 2018 Apr 27;81(4):949-956. |
3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine
CAS: 2226941-29-1 F: C28H24N4O4 W: 480.51
3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine (Compound 7) is an inhibitor of protein kinases, with I
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