PeptideDB

3α,7α-Dihydroxycoprostanic acid-d3

CAS: 338976-76-4 F: C27H43D3O4 W: 437.67

3α,7α-Dihydroxycoprostanic acid-d3is the deuterium labeled3α,7α-Dihydroxycoprostanic acid(HY-113097). 3α,7α-Dihydr
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Bioactivity 3α,7α-Dihydroxycoprostanic acid-d3is the deuterium labeled3α,7α-Dihydroxycoprostanic acid(HY-113097)[1]. 3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid[2].
Invitro 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。
Name 3α,7α-Dihydroxycoprostanic acid-d3
CAS 338976-76-4
Formula C27H43D3O4
Molar Mass 437.67
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.