3-Phenylpropyl isothiocyanate_product_DataBase

Bioactivity	3-Phenylpropyl isothiocyanate has a stronger inhibitory effect on N-nitrosomethyl-benzylamine (NMBA) tumorigenesis. 3-Phenylpropyl isothiocyanate has chemopreventive effects[1][2].
In Vivo	3-Phenylpropyl isothiocyanate (5, 1, or 0.2 µmol; gavage; A/J mice; daily for 4 consecutive days prior to administration of 10 µmol of NNK by i.p. injection) effectively inhibited NNK-induced lung tumors.
Name	3-Phenylpropyl isothiocyanate
CAS	2627-27-2
Formula	C10H11NS
Molar Mass	177.27
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Morse MA, et al. Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice. Cancer Res. 1991;51(7):1846-1850. [2]. Nishikawa A, et al. Chemopreventive effects of 3-phenylpropyl isothiocyanate on hamster lung tumorigenesis initiated with N-nitrosobis(2-oxopropyl)amine. Jpn J Cancer Res. 1996;87(2):122-126.

PeptideDB