| Bioactivity | 3-OH-Kynurenamine is a lateral metabolite in Tryptophan (HY-N0623) metabolism. 3-OH-Kynurenamine induces a concentration-dependent AhR activation, around 6.5 times higher than L-kynurenine (HY-104026). 3-OH-Kynurenamine confers immunosuppressive properties on dendritic cells (DCs). 3-OH-Kynurenamine can be used for psoriasis research[1]. |
| In Vivo | 3-OH-Kynurenamine（50 mg/kg，腹腔注射，每日，持续 7 天）可减少小鼠牛皮癣的临床和组织学表现，并减轻肾毒性肾炎 (NTN)[1]。 |
| Name | 3-OH-Kynurenamine |
| CAS | 99362-47-7 |
| Formula | C9H12N2O2 |
| Molar Mass | 180.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Laura SANTAMBROGIO. Immunoregulatory role of 3-oh-kynurenamine and uses thereof. Patent, WO2019178013A1. |
3-OH-Kynurenamine
CAS: 99362-47-7 F: C9H12N2O2 W: 180.20
3-OH-Kynurenamine is a lateral metabolite in Tryptophan (HY-N0623) metabolism. 3-OH-Kynurenamine induces a concentration
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