| Bioactivity | 3-Methyl-2-oxovaleric acid-d8 (sodium) is the deuterium labeled 3-Methyl-2-oxovaleric acid. 3-Methyl-2-oxovaleric acid is a neurotoxin, an acidogen, and a metabotoxin, and also an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids[1]. |
| Invitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| Name | 3-Methyl-2-oxovaleric acid-d8 (sodium) |
| CAS | 1795037-03-4 |
| Formula | C6HD8NaO3 |
| Molar Mass | 160.17 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. |
3-Methyl-2-oxovaleric acid-d8 (sodium)
CAS: 1795037-03-4 F: C6HD8NaO3 W: 160.17
3-Methyl-2-oxovaleric acid-d8 (sodium) is the deuterium labeled 3-Methyl-2-oxovaleric acid. 3-Methyl-2-oxovaleric acid i
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