| Bioactivity | 3-MeOARh-NTR is an activatable imaging probe with high selectivity, and good stability. 3-MeOARh-NTR possesses high selectivity and high signal-to-noise ratio for nitroreductase (NTR) detection, and serves as an efficient molecular tool for endogenous NTR detection[1]. |
| Invitro | 3-MeOARh-NTR（10 μM，30 分钟；细胞在 20% O2 和 10% O2 中孵育 12 小时）在氧含量降低的活 HeLa 细胞中产生强烈的荧光信号[1]。3-MeOARh-NTR（10 μM，30 分钟）对小鼠肾脏组织产生荧光成像（λex=488 nm；λem=510-590 nm）。3-MeOARh-NTR 是通过 NTR 检测评估肾脏缺氧的有效探针[1]。 |
| Name | 3-MeOARh-NTR |
| Formula | C33H30N3O8+ |
| Molar Mass | 596.61 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Guo H, et al. Designing a Brightness-Restored Rhodamine Derivative by the Ortho-Compensation Effect for Assessing Drug-Induced Acute Kidney Injury. Anal Chem. 2023 May 2;95(17):6863-6870. |