| Bioactivity | 3-Hydroxypyridine-d4 is the deuterium labeled 3-Hydroxypyridine[1]. 3-Hydroxypyridine is isolated from Bamboo grass. 3-Hydroxypyridine derivatives are structural analogues of vitamin B6 and have a wide range of pharmacological properties, such as antioxidant properties[2][3]. |
| Invitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| Name | 3-Hydroxypyridine-d4 |
| Formula | C5HD4NO |
| Molar Mass | 99.12 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Atsushi Endo, et al. Bamboo grass extract and use of the same extract. JP2006298766A [3]. L D Lukyanova, et al. Energotropic effect of succinate-containing derivatives of 3-hydroxypyridine. Bull Exp Biol Med. 2009 Oct148(4):587-91. |