Bioactivity | 3-HTC is a chemical fluorescent probe. 3-HTC reacts reversibly with thiols and disulfides, and can be used to measure dynamic GSH/GSSH ratios in vitro as well as to monitor the reversible redox status of whole cell lysates (λmax: 448 nm in its reduced thiolate form, and a λmax 370-410 nm for the oxidized mixed disulfide)[1]. |
Name | 3-HTC |
CAS | 1356543-39-9 |
Formula | C16H9NO2S2 |
Molar Mass | 311.38 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Reddie KG, et al. Fluorescent coumarin thiols measure biological redox couples. Org Lett. 2012 Feb 3;14(3):680-3. |