| Bioactivity | 3'-Fluoro-3'-deoxythymidine (Alovudine) is a marker of DNA synthesis that is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer. 3'-Fluoro-3'-deoxythymidine shows anti-orthopoxvirus activity[1][2]. | ||||||||||||
| Name | 3'-Fluoro-3'-deoxythymidine | ||||||||||||
| CAS | 25526-93-6 | ||||||||||||
| Formula | C10H13FN2O4 | ||||||||||||
| Molar Mass | 244.22 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Challapalli A, et al. 3'-Deoxy-3'-18F-fluorothymidine positron emission tomography as an early predictor of disease progression in patients with advanced and metastatic pancreatic cancer. Eur J Nucl Med Mol Imaging. 2015 May;42(6):831-40. [2]. Smee DF, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52. |
3'-Fluoro-3'-deoxythymidine
CAS: 25526-93-6 F: C10H13FN2O4 W: 244.22
3'-Fluoro-3'-deoxythymidine (Alovudine) is a marker of DNA synthesis that is less susceptible to inflammatory changes th
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