Bioactivity | 3-Epideoxycholic acid is the microbial metabolite of Deoxycholic acid (HY-N0593). 3-Epideoxycholic acid targets FXR of dendritic cells, reduces their immunostimulatory properties, promotes the generation of Treg cells, and exhibits anti-inflammatory activity. 3-Epideoxycholic acid promotes the growth of bacteria Bacteroides[1][2]. | |||||||||
CAS | 570-63-8 | |||||||||
Formula | C24H40O4 | |||||||||
Molar Mass | 392.57 | |||||||||
Appearance | 固体 | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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Reference | [1]. Campbell C, et al., Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells. Nature. 2020 May;581(7809):475-479. [2]. Devlin AS, et al., A biosynthetic pathway for a prominent class of microbiota-derived bile acids. Nat Chem Biol. 2015 Sep;11(9):685-90. |