PeptideDB

3-Epideoxycholic acid

CAS: 570-63-8 F: C24H40O4 W: 392.57

3-Epideoxycholic acid is the microbial metabolite of Deoxycholic acid (HY-N0593). 3-Epideoxycholic acid targets FXR of d
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Bioactivity 3-Epideoxycholic acid is the microbial metabolite of Deoxycholic acid (HY-N0593). 3-Epideoxycholic acid targets FXR of dendritic cells, reduces their immunostimulatory properties, promotes the generation of Treg cells, and exhibits anti-inflammatory activity. 3-Epideoxycholic acid promotes the growth of bacteria Bacteroides[1][2].
CAS 570-63-8
Formula C24H40O4
Molar Mass 392.57
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Campbell C, et al., Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells. Nature. 2020 May;581(7809):475-479. [2]. Devlin AS, et al., A biosynthetic pathway for a prominent class of microbiota-derived bile acids. Nat Chem Biol. 2015 Sep;11(9):685-90.