| Bioactivity | 3-Aminobenzoic acid (3-ABA) is an orally active anti-inflammatory agent targeting the tight junction (TJ) regulatory pathways in intestinal epithelial cells. 3-Aminobenzoic acid improves intestinal inflammation by enhancing intestinal barrier integrity and reducing epithelial permeability. It can be used in studies related to improving gut health. Additionally, 3-Aminobenzoic acid analogs can act as γ-aminobutyric acid transaminase (GABA-AT) inhibitors, exhibiting anticonvulsant effects[1][2][3][4]. | ||||||
| CAS | 99-05-8 | ||||||
| Formula | C7H7NO2 | ||||||
| Molar Mass | 137.14 | ||||||
| Appearance | 固体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Store at room temperature 3 years
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| Reference | [1]. Tanaka M, et al. Exploring 3-Aminobenzoic Acid as a Therapeutic Dietary Component for Enhancing Intestinal Barrier Integrity in Ulcerative Colitis[J]. bioRxiv, 2024: 2024.08. 18.608525. [2]. Tanaka M, et al. P095 Accelerated degradation of gut barrier-protecting 3-aminobenzoic acid exacerbate colitis in Inflammatory Bowel Disease[J]. Journal of Crohn's and Colitis, 2024, 18(Supplement_1): i374-i374. [3]. Kumar A, et al. 3-Aminobenzoic Acid Analogues as a Novel GABA-at Inhibitors: Synthesis, Pharmacological Evaluation and Molecular Docking Studies[J]. Drug Discovery and Development, 2014, 1(2): 110-120. |
3-Aminobenzoic acid
CAS: 99-05-8 F: C7H7NO2 W: 137.14
3-Aminobenzoic acid (3-ABA) is an orally active anti-inflammatory agent targeting the tight junction (TJ) regulatory pat
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