Bioactivity | 3-Amino-1,2,4-triazine is an inhibitor of NO synthase, and also inhibits nitrite secretion[1]. |
Invitro | 3-Amino-1,2,4-triazine (50 mM; 7 h) inhibits NO synthase activity in cytosolic extracts of activated cells[1].3-Amino-1,2,4-triazine (5-50 mM; 24 h) inhibits both nitrite secretion and parasite killing by activated macrophages[1]. |
Name | 3-Amino-1,2,4-triazine |
CAS | 1120-99-6 |
Formula | C3H4N4 |
Molar Mass | 96.09 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. Buchmüller-Rouiller Y, et al. 3-amino-1,2,4-triazole inhibits macrophage NO synthase. Biochem Biophys Res Commun. 1992 Feb 28;183(1):150-5. |