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3-Amino-1,2,4-triazine

CAS: 1120-99-6 F: C3H4N4 W: 96.09

3-Amino-1,2,4-triazine is an inhibitor of NO synthase, and also inhibits nitrite secretion.
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Bioactivity 3-Amino-1,2,4-triazine is an inhibitor of NO synthase, and also inhibits nitrite secretion[1].
Invitro 3-Amino-1,2,4-triazine (50 mM; 7 h) inhibits NO synthase activity in cytosolic extracts of activated cells[1].3-Amino-1,2,4-triazine (5-50 mM; 24 h) inhibits both nitrite secretion and parasite killing by activated macrophages[1].
Name 3-Amino-1,2,4-triazine
CAS 1120-99-6
Formula C3H4N4
Molar Mass 96.09
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Reference [1]. Buchmüller-Rouiller Y, et al. 3-amino-1,2,4-triazole inhibits macrophage NO synthase. Biochem Biophys Res Commun. 1992 Feb 28;183(1):150-5.