Bioactivity | 3,4-Diphenyl-5H-furan-2-one is a natural compound isolated from the endophytic fungus Aspergillus flavipes AIL8 derived from the mangrove plant Acanthus ilicifolius. 3,4-Diphenyl-5H-furan-2-one is a derivative of 2,3-diphenyltetrahydrofuran (DPTF), which is a COX-2 inhibitor. 3,4-Diphenyl-5H-furan-2-one can be used as a lead compound for inflammation and pain[1][2]. |
CAS | 5635-16-5 |
Formula | C16H12O2 |
Molar Mass | 236.27 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bai Z Q, et al. New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius[J]. Fitoterapia, 2014, 95: 194-202. [2]. Singh P, et al. 2, 3-Diphenyltetrahydrofurans (DPTF)-A new class of stereogenic diarylheterocycles as potential COX-2 inhibitors-Computational evaluation of COX-2-DPTF binding behaviour[J]. 2006. |