| Bioactivity | 3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) function in diabetic rat mesenteric arteries[1]. |
| Invitro | 3',4'-Dihydroxyflavonol (DiOHF) acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling to improve endothelial function[1].3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized third-order branches of rat mesenteric arteries[2]. |
| Name | 3',4'-Dihydroxyflavonol |
| CAS | 6068-78-6 |
| Formula | C15H10O5 |
| Molar Mass | 270.24 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Leo CH, et al. 3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries. PLoS One. 2011;6(6):e20813. [2]. Kim HY, et al. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized rat mesenteric artery. Naunyn Schmiedebergs Arch Pharmacol. 2012 Feb;385(2):191-202. |
3',4'-Dihydroxyflavonol
CAS: 6068-78-6 F: C15H10O5 W: 270.24
3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) fun
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