Bioactivity | 3,4-Dihydroxyamphetamine (α-Methyldopamine) (hydrochloride) is a secondary metabolite of 3,4-Methylenedioxymethamphetamine (MDMA). 3, 4-dihydroxyamphetamine (hydrochloride) is cytotoxic to rat hepatocytes. 3, 4-dihydroxyamphetamine (hydrochloride) is also used in the study of high blood pressure[1][2][3]. |
CAS | 828-06-8 |
Formula | C9H14ClNO2 |
Molar Mass | 203.67 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Schwaninger AE, et al. Urinary excretion kinetics of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and its phase I and phase II metabolites in humans following controlled MDMA administration. Clin Chem. 2011 Dec;57(12):1748-56. [2]. Carvalho M, et al. Hepatotoxicity of 3,4-methylenedioxyamphetamine and alpha-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates. Arch Toxicol. 2004 Jan;78(1):16-24. [3]. Waldmeier P, et al. On the role of alpha-methyldopamine in the antihypertensive effect of alpha-methyldopa. Naunyn Schmiedebergs Arch Pharmacol. 1975;289(3):303-14. |