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2′-O-Methyluridine-d3

CAS: F: C10H11D3N2O6 W: 261.25

2′-O-Methyluridine-d3 is deuterium labeled 2′-O-Methyluridine (HY-W011824). 2'-O-methyluridine is found in rRNA, snRNA
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Bioactivity 2′-O-Methyluridine-d3 is deuterium labeled 2′-O-Methyluridine (HY-W011824). 2'-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota.
Invitro 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 0 --> 2′-O-Methyluridine-d3 相关抗体:
Name 2′-O-Methyluridine-d3
Formula C10H11D3N2O6
Molar Mass 261.25
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Aučynaitė A, et al. Identification of a 2'-O-Methyluridine Nucleoside Hydrolase Using the Metagenomic Libraries. Molecules. 2018;23(11):2904. Published 2018 Nov 7.