| Bioactivity | 2′-O-Methyl-8-methyl guanosine (m8Gm) is a Z-form RNA stabilizer. 2′-O-Methyl-8-methyl guanosine can markedly stabilize the Z-RNA at low salt conditions[1]. m8Gm-contained oligonucleotides stabilizethe Z-DNA under low salt conditions[2]. | ||||||||||||
| Name | 2′-O-Methyl-8-methyl guanosine | ||||||||||||
| CAS | 2306782-64-7 | ||||||||||||
| Formula | C12H17N5O5 | ||||||||||||
| Molar Mass | 311.29 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Balasubramaniyam T, Ishizuka T, Xiao CD, Bao HL, Xu Y. 2'-O-Methyl-8-methylguanosine as a Z-Form RNA Stabilizer for Structural and Functional Study of Z-RNA. Molecules. 2018;23(10):2572. [2]. Balasubramaniyam T, Ishizuka T, Xu Y. Stability and properties of Z-DNA containing artificial nucleobase 2'-O-methyl-8-methyl guanosine. Bioorg Med Chem. 2019;27(2):364-369. |
2′-O-Methyl-8-methyl guanosine
CAS: 2306782-64-7 F: C12H17N5O5 W: 311.29
2′-O-Methyl-8-methyl guanosine (m8Gm) is a Z-form RNA stabilizer. 2′-O-Methyl-8-methyl guanosine can markedly stabiliz
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