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2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine

CAS: 139878-36-7 F: C21H39FN2O5Si2 W: 474.71

2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad ant
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Bioactivity 2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Name 2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine
CAS 139878-36-7
Formula C21H39FN2O5Si2
Molar Mass 474.71
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.