| Bioactivity | 2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and Drug Administration for use in combination with valsartan for the treatment of patients with heart failure. | ||||||||||||
| Name | 2S,4R-Sacubitril | ||||||||||||
| CAS | 2307668-79-5 | ||||||||||||
| Formula | C25H31NO5 | ||||||||||||
| Molar Mass | 425.52 | ||||||||||||
| Appearance | Oil | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9. |
2S,4R-Sacubitril
CAS: 2307668-79-5 F: C25H31NO5 W: 425.52
2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and Drug Administration for use in co
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