| Bioactivity | 2F5 epitope, a peptide gp41 (659-671), comprises the entire epitope for one of the three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates and is the only such epitope that is sequential. 2F5 epitope is recognized by broadly neutralizing antibodies 2F5[1][2]. |
| Name | 2F5 epitope |
| CAS | 470704-11-1 |
| Shortening | ELLELDKWASLWN |
| Formula | C76H113N17O22 |
| Molar Mass | 1616.81 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zohar Biron, et al. A monomeric 3(10)-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41. Biochemistry. 2002 Oct 22;41(42):12687-96. [2]. Yougang Zhai, et al. Bovine papillomavirus-like particles presenting conserved epitopes from membrane-proximal external region of HIV-1 gp41 induced mucosal and systemic antibodies. Vaccine. 2013 Nov 4;31(46):5422-9. |
2F5 epitope
CAS: 470704-11-1 F: C76H113N17O22 W: 1616.81
2F5 epitope, a peptide gp41 (659-671), comprises the entire epitope for one of the three known antibodies capable of neu
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