| Bioactivity | 28-Homobrassinolide is a phytosteroid. 28-Homobrassinolide can be used for the research of cholesterol and glucose homeostasis[1]. |
| Invitro | 28-Homobrassinolide (5-20 μM) 表明 HepG2 细胞中的葡萄糖利用以及 ABCA1 和 SREBP2 蛋白表达增加了 2 倍[1]。28-Homobrassinolide 降低组织葡萄糖和胆固醇水平，增加胆固醇水平和组织己糖激酶活性[1]。 Cell Cytotoxicity Assay[1] Cell Line: |
| In Vivo | 28-HB（1-20 μg/天；持续 6 周）显示高脂肪饮食喂养的 C57BL/6 小鼠的主动脉脂肪沉积和血清标志物水平显着降低[1]。 Animal Model: |
| Name | 28-Homobrassinolide |
| CAS | 82373-95-3 |
| Formula | C29H50O6 |
| Molar Mass | 494.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Victor Mukherjee, et al. Phytosteroid 28-homobrassinolide targets cholesterol and glucose homeostasis implicating ABCA1 and SREBP role in regulation. Steroids. 2021 Jan;165:108756. |