Bioactivity | 28-Epirapamycin is an impurity of Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells[1]. | ||||||||||||
Name | 28-Epirapamycin | ||||||||||||
CAS | 253431-35-5 | ||||||||||||
Formula | C51H79NO13 | ||||||||||||
Molar Mass | 914.17 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Edwards SR, et al. The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain. J Biol Chem. 2007;282(18):13395-13401. |