Bioactivity | 20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway. |
CAS | 57930-92-4 |
Formula | C20H34O6 |
Molar Mass | 370.48 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Devereux, et al. Metabolism of prostaglandin PG-F2α by freshly isolated alveolar type II cells from lungs of adult male or pregnant rabbits. Prostaglandins Leukot. Med. 27, 43-52 (1987). |