Bioactivity | 2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively. 2-TEDC can be used for the research of atheroscrelosi[1]. | ||||||||||||
Target | IC50: 0.09 μM (5-lipoxygenase); 0.013 μM (12-lipoxygenase); 0.5 μM (15-lipoxygenase). | ||||||||||||
Invitro | 2-TEDC can potent inhibit 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively[1]. | ||||||||||||
Name | 2-TEDC | ||||||||||||
CAS | 132465-10-2 | ||||||||||||
Formula | C16H13NO4S | ||||||||||||
Molar Mass | 315.34 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. H Cho, et al. Novel caffeic acid derivatives: extremely potent inhibitors of 12-lipoxygenase. J Med Chem. 1991 Apr;34(4):1503-5. |