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2-Phenylacetophenone

CAS: 451-40-1 F: C14H12O W: 196.24

2-Phenylacetophenone has broad-spectrum efflux pump inhibition activity. 2-Phenylacetophenone is a benzoin derivative us
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Bioactivity 2-Phenylacetophenone has broad-spectrum efflux pump inhibition activity. 2-Phenylacetophenone is a benzoin derivative used as a photoinitiator in vinyl polymerization[1].
Invitro 2-Phenylacetophenone displays antibacterial activity against B. subtilis, M. smegmatis, and M. aurum with MICs of 500 µg/mL[1]. 2-Phenylacetophenone (1000 µg/mL) inhibits biofilm formation for M. smegmatis[1].
Name 2-Phenylacetophenone
CAS 451-40-1
Formula C14H12O
Molar Mass 196.24
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Hellewell L, et al. Chalcones, stilbenes and ketones have anti-infective properties via inhibition of bacterial drug-efflux and consequential synergism with antimicrobial agents. Access Microbiol. 2020 Feb 18;2(4):acmi000105.