Bioactivity | 2-Phenylacetophenone has broad-spectrum efflux pump inhibition activity. 2-Phenylacetophenone is a benzoin derivative used as a photoinitiator in vinyl polymerization[1]. | ||||||||||||
Invitro | 2-Phenylacetophenone displays antibacterial activity against B. subtilis, M. smegmatis, and M. aurum with MICs of 500 µg/mL[1]. 2-Phenylacetophenone (1000 µg/mL) inhibits biofilm formation for M. smegmatis[1]. | ||||||||||||
Name | 2-Phenylacetophenone | ||||||||||||
CAS | 451-40-1 | ||||||||||||
Formula | C14H12O | ||||||||||||
Molar Mass | 196.24 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Hellewell L, et al. Chalcones, stilbenes and ketones have anti-infective properties via inhibition of bacterial drug-efflux and consequential synergism with antimicrobial agents. Access Microbiol. 2020 Feb 18;2(4):acmi000105. |