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2-Methyl-5-HT hydrochloride

CAS: 845861-49-6 F: C11H15ClN2O W: 226.70

2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonis
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Bioactivity 2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT hydrochloride is shown to display anti-depressive-like effects[1].
In Vivo 2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) (i.p.; 3 mg/kg; 45 minutes) significantly decreases time of immobility as compared to controls thus showing anti-depressive-like effects[1]. Animal Model:
Name 2-Methyl-5-HT hydrochloride
CAS 845861-49-6
Formula C11H15ClN2O
Molar Mass 226.70
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Sumaya IC, et al. Differential effects of a short-term high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist, ondansetron, the 5-HT3 receptor agonist, 2-methyl-5-HT, and the SSRI, fluoxetine. Pharmacol Biochem B