| Bioactivity | 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[1]. | ||||||||||||
| Invitro | 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning[1].2-Ketoglutaric acid acts as precursor for the synthesis of amino acids and nucleotides[2]. | ||||||||||||
| Name | 2-Ketoglutaric acid | ||||||||||||
| CAS | 328-50-7 | ||||||||||||
| Formula | C5H6O5 | ||||||||||||
| Molar Mass | 146.10 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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2-Ketoglutaric acid
CAS: 328-50-7 F: C5H6O5 W: 146.10
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-K
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