| Bioactivity | 2-Ketoglutaric acid potassium (Alpha-Ketoglutaric acid potassium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid potassium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid potassium is a reversible inhibitor of tyrosinase with an IC50 value of 15 mM[1][2]. |
| CAS | 997-43-3 |
| Formula | C5H6KO5 |
| Molar Mass | 185.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Huergo LF, et al. The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite. Microbiol Mol Biol Rev. 2015 Dec;79(4):419-35. [2]. Gou L, et al. The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. Int J Biol Macromol. 2017 Dec;105(Pt 3):1654-1662. |
2-Ketoglutaric acid potassium
CAS: 997-43-3 F: C5H6KO5 W: 185.20
2-Ketoglutaric acid potassium (Alpha-Ketoglutaric acid potassium) is an intermediate in the production of ATP or GTP in
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