| Bioactivity | 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity[1][3]. | |||||||||
| Invitro | 2-Hydroxyestradiol induces phenotypical changes indicative of neoplastic transformation[1].2-Hydroxyestradiol (2-OHE2) is capable of in vitro transforming a HBEC, MCF-10F cell line, that is estrogen receptor-a (ERα) negative and ERβ positive[1].2-Hydroxyestradiol induces oxidative DNA damage and apoptosis in human mammary epithelial cells[3]. | |||||||||
| Name | 2-Hydroxyestradiol | |||||||||
| CAS | 362-05-0 | |||||||||
| Formula | C18H24O3 | |||||||||
| Molar Mass | 288.38 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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2-Hydroxyestradiol
CAS: 362-05-0 F: C18H24O3 W: 288.38
2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and r
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