Bioactivity | 2-Hydroxy-3-methoxychalcone is a methoxy-derivative of 2'-Hydroxychalcone with an anticancer activity[1]. |
Invitro | 2-Hydroxy-3-methoxychalcone (TJ3)(10μM 和 25μM)显着降低 SW480 细胞分泌的 MIF 浓度,这与 ICAM-1 的下调相关。22-Hydroxy-3-methoxychalcone (25μM) 可增加 SW480 和 SW620 癌细胞中 IL-8 的浓度[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> 2-Hydroxy-3-methoxychalcone 相关抗体: |
CAS | 7146-86-3 |
Formula | C16H14O3 |
Molar Mass | 254.28 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Joanna Bronikowska, et al. The modulating effect of methoxy-derivatives of 2'-hydroxychalcones on the release of IL-8, MIF, VCAM-1 and ICAM-1 by colon cancer cells. Biomed Pharmacother. 2022 Jan:145:112428. |