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2-Hydroxy-3-methoxychalcone

CAS: 7146-86-3 F: C16H14O3 W: 254.28

2-Hydroxy-3-methoxychalcone is a methoxy-derivative of 2'-Hydroxychalcone with an anticancer activity.
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Bioactivity 2-Hydroxy-3-methoxychalcone is a methoxy-derivative of 2'-Hydroxychalcone with an anticancer activity[1].
Invitro 2-Hydroxy-3-methoxychalcone (TJ3)(10μM 和 25μM)显着降低 SW480 细胞分泌的 MIF 浓度,这与 ICAM-1 的下调相关。22-Hydroxy-3-methoxychalcone (25μM) 可增加 SW480 和 SW620 癌细胞中 IL-8 的浓度[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> 2-Hydroxy-3-methoxychalcone 相关抗体:
CAS 7146-86-3
Formula C16H14O3
Molar Mass 254.28
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Joanna Bronikowska, et al. The modulating effect of methoxy-derivatives of 2'-hydroxychalcones on the release of IL-8, MIF, VCAM-1 and ICAM-1 by colon cancer cells. Biomed Pharmacother. 2022 Jan:145:112428.