PeptideDB

2-Hydrazinobenzothiazole

CAS: 615-21-4 F: C7H7N3S W: 165.22

2-Hydrazinobenzothiazole is a potent IDO1 inhibitor with an IC50 of 8 μM. 2-hydrazinobenzothiazole interacts with the I
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Bioactivity 2-Hydrazinobenzothiazole is a potent IDO1 inhibitor with an IC50 of 8 μM. 2-hydrazinobenzothiazole interacts with the IDO1 haem through hydrazine. 2-hydrazinobenzothiazole has the potential for immune system related diseases research[1].
CAS 615-21-4
Formula C7H7N3S
Molar Mass 165.22
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Reference [1]. Sai-Parng S Fung, et al. Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1). Bioorg Med Chem. 2013 Dec 15;21(24):7595-603.