| Bioactivity | 2-Ethylhexyl diphenyl phosphate is an organophosphate flame retardants (OPFRs) and a PPARG agonist (EC20: 2.04 µM). 2-Ethylhexyl diphenyl phosphate also inhibits ERRγ transcriptional activity (IC50: 1.3 µM). 2-Ethylhexyl diphenyl phosphate upregulates 3β-HSD1, human chorionic gonadotropin (hCG) and progesterone secretion. 2-Ethylhexyl diphenyl phosphate can be used in studies of female reproduction and fetal development[1][2]. |
| CAS | 1241-94-7 |
| Formula | C20H27O4P |
| Molar Mass | 362.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hu W, et al. Activation of Peroxisome Proliferator-Activated Receptor Gamma and Disruption of Progesterone Synthesis of 2-Ethylhexyl Diphenyl Phosphate in Human Placental Choriocarcinoma Cells: Comparison with Triphenyl Phosphate. Environ Sci Technol. 2017 Apr 4;51(7):4061-4068. [2]. Cao L Y, et al. Organophosphate esters bind to and inhibit estrogen-related receptor γ in cells. Environmental Science & Technology Letters, 2018, 5(2): 68-73. |
2-Ethylhexyl diphenyl phosphate
CAS: 1241-94-7 F: C20H27O4P W: 362.41
2-Ethylhexyl diphenyl phosphate is an organophosphate flame retardants (OPFRs) and a PPARG agonist (EC20: 2.04 µM). 2-E
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