| Bioactivity | 2-Cyanoethylalsterpaullone (compound 7) is an Alsterpaullone (HY-108359) derivative, which exhibits potent and selective inhibitory activities against CDK1/Cyclin B and GSK-3β (GSK-3β: IC50=0.8 nM; CDK1/Cyclin B: IC50=0.23 nM)[1]. |
| CAS | 852527-97-0 |
| Formula | C19H14N4O3 |
| Molar Mass | 346.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kunick, et al. "Structure‐aided optimization of kinase inhibitors derived from alsterpaullone." ChemBioChem 6.3 (2005): 541-549. |
2-Cyanoethylalsterpaullone
CAS: 852527-97-0 F: C19H14N4O3 W: 346.34
2-Cyanoethylalsterpaullone (compound 7) is an Alsterpaullone (HY-108359) derivative, which exhibits potent and selective
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