2-Aminoflubendazole-13C6_product_DataBase

Bioactivity	2-Aminoflubendazole-13C6 is the 13C6 labeled 2-Aminoflubendazole. 2-Aminoflubendazole is the metabolite of Benzimidazoles. Benzimidazoles (BZ) are a class of drugs with activities against fungi, protozoa, and helminthes.
Invitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name	2-Aminoflubendazole-13C6
Formula	C813C6H10FN3O
Molar Mass	261.20
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Marija Denžić Lugomer, et al. Determination of benzimidazole residues and their metabolites in raw milk using high performance liquid chromatography-diode array detection. [3]. Jaeger LH, et al. Status of benzimidazole resistance in intestinal nematode populations of livestock in Brazil: a systematic review. BMC Vet Res. 2017;13(1):358. Published 2017 Nov 25.

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