| Bioactivity | 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3)[1][2][3]. | ||||||||||||
| Name | 2-Aminoethyl diphenylborinate | ||||||||||||
| CAS | 524-95-8 | ||||||||||||
| Formula | C14H16BNO | ||||||||||||
| Molar Mass | 225.09 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Ma S, et al. Effect of Wilforine on the Calcium Signaling Pathway in Mythimna separata Walker MyocytesUsing the Calcium Imaging Technique. J Agric Food Chem. 2019 Nov 27. [2]. Boyacı MG, et al. Effects of 2-Aminoethyl Diphenylborinate, a Modulator of Transient Receptor Potential and OraiChannels in Subarachnoid Hemorrhage: An Experimental Study. [3]. Takahashi K, et al. Molecular mechanism of 2-APB-induced Ca²⁺ influx in external acidification in PC12. Exp Cell Res. 2014 May 1;323(2):337-45. |
2-Aminoethyl diphenylborinate
CAS: 524-95-8 F: C14H16BNO W: 225.09
2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R. 2-Aminoethyl diphenylborinate also inhibits
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