Bioactivity | 2-APQC is a SIRT3 activator with the Kd value of 2.756 μM. 2-APQC improves heart failure in vitro and in vivo[1]. |
CAS | 500271-63-6 |
Formula | C23H24FN5O |
Molar Mass | 405.47 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Peng F, et al. 2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis. Signal Transduct Target Ther. 2024;9(1):133. |