Bioactivity | 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm[1]. |
Invitro | 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) contains two distinct phosphodiester linkages, one between 2′-OH of GMP and 5′-phosphate of AMP, and the other between 3′-OH of AMP and 5′-phosphate of GMP[1]. |
Name | 2',3'-cGAMP |
CAS | 1441190-66-4 |
Formula | C20H24N10O13P2 |
Molar Mass | 674.41 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |