Bioactivity | 2,3,4,6,8-Pentahydroxy-1-methylxanthone is a xanthone derivative of Wardomyces anomalus. 2,3,4,6,8-Pentahydroxy-1-methylxanthone shows significant antioxidant activities. 2,3,4,6,8-Pentahydroxy-1-methylxanthone is inhibitors of p56lck tyrosine kinase. 2,3,4,6,8-Pentahydroxy-1-methylxanthone can be used to treat cardiovascular disease[1]. |
Target | p56 lck |
Invitro | 2,3,4,6,8-Pentahydroxy-1-methylxanthone (1~50µM, 50µg/mL ox-LDL, 6h) 在人脐静脉内皮细胞对 ox-LDL 诱导的细胞凋亡具有保护作用[2]。2,3,4,6,8-Pentahydroxy-1-methylxanthone (1~50µM, 50µg/mL ox-LDL, 6h) 在人脐静脉内皮细胞抑制 ox-LDL 诱导的 VECs粘附分子表达[2]。2,3,4,6,8-Pentahydroxy-1-methylxanthone (1~50µM, 50µg/mL ox-LDL, 6h) 在人脐静脉内皮细胞对ox-LDL 引起的氧化损伤有保护作用[2]。 0 --> 2,3,4,6,8-Pentahydroxy-1-methylxanthone 相关抗体: Apoptosis Analysis[2] Cell Line: |
Name | 2,3,4,6,8-Pentahydroxy-1-methylxanthone |
CAS | 548740-87-0 |
Formula | C14H10O7 |
Molar Mass | 290.23 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Abdel-Lateff A, et al. Two new xanthone derivatives from the algicolous marine fungus Wardomyces anomalus. J Nat Prod. 2003 May;66(5):706-8. [2]. Hou JR, et al. Protective Effect of Flavonoids from a Deep-Sea-Derived Arthrinium sp. against ox-LDL-Induced Oxidative Injury through Activating the AKT/Nrf2/HO-1 Pathway in Vascular Endothelial Cells. Mar Drugs. 2021 Dec 18;19(12):712. |