| Bioactivity | 1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion[1]. |
| Invitro | 1 alpha, 25(OH)2D3 is an important negative regulator of parathyroid hormone (PTH) gene transcription[1]. In ROS 17/2.8 cells, 1α-OHD3 (10 μM) not only metabolized into 1αOH-3-epi-D3 and 1α,25(OH)2D3 but also 1α,25(OH)2-3-epi-D3[2]. |
| Name | 1α-Hydroxy-3-epi-vitamin D3 |
| CAS | 58028-00-5 |
| Formula | C27H44O2 |
| Molar Mass | 400.64 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. A J Brown, et al. 1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion. J Cell Biochem. 1999 Apr 1;73(1):106-13. [2]. Alex J Brown, et al. Isolation and identification of 1alpha-hydroxy-3-epi-vitamin D3, a potent suppressor of parathyroid hormone secretion. J Cell Biochem |
1α-Hydroxy-3-epi-vitamin D3
CAS: 58028-00-5 F: C27H44O2 W: 400.64
1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyro
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