16,16-Dimethylprostaglandin E1_product_DataBase

Bioactivity	16,16-Dimethylprostaglandin E1 is a PGE1 analog, induces bronchoconstrict and vascular smooth muscle contractions and suppresses the indomethacin induced cellular elongation[1][2][3].
In Vivo	16,16-Dimethylprostaglandin E1 (1 μg/kg•min 共 30 分钟) 可加速 Sprague Dawley 大鼠急性出血后血压和心率速率恢复，增加 catecholamine 周转率，提高血浆中肾上腺素和去甲肾上腺素水平[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS	41692-15-3
Formula	C22H38O5
Molar Mass	382.53
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Feuerstein G, et al., Prostaglandins, catecholamines, and cardiovascular responses to hemorrhage. Am J Physiol. 1981 Mar;240(3):R166-74. [2]. Jumblatt MM, et al., Prostaglandin E2 effects on corneal endothelial cyclic adenosine monophosphate synthesis and cell shape are mediated by a receptor of the EP2 subtype. Invest Ophthalmol Vis Sci. 1991 Feb;32(2):360-5. [3]. Strandberg K, et al., Bronchial effects of some prostaglandin E and F analogues. Acta Physiol Scand. 1977 Jun;100(2):172-81.

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