| Bioactivity | 14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation. | ||||||||||||
| Invitro | 14-deoxy-11,12-didehydroandrographolide, a naturally occurring noncytotoxic analogue of Andrographolide, effectively reduces Ovalbumin (OVA)-induced inflammatory cell recruitment into bronchoalveolar lavage (BAL) fluid, IL-4, IL-5, IL-13, and eotaxin production, serum IgE synthesis, pulmonary eosinophilia, mucus hypersecretion, mast cell degranulation, and airway hyper-responsiveness (AHR) in a mouse asthma model, probably via inhibition of NF-κB activity[1]. | ||||||||||||
| Name | 14-Deoxy-11,12-didehydroandrographolide | ||||||||||||
| CAS | 42895-58-9 | ||||||||||||
| Formula | C20H28O4 | ||||||||||||
| Molar Mass | 332.43 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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14-Deoxy-11,12-didehydroandrographolide
CAS: 42895-58-9 F: C20H28O4 W: 332.43
14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhib
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