PeptideDB

14-3-3σ/ERα stabilizer-1

CAS: F: C25H35Cl2N3O3 W: 496.47

14-3-3σ/ERα stabilizer-1 (Compound 181) is a covalent 14-3-3σ/ERα stabilizer. 14-3-3σ/ERα stabilizer-1 can be used
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity 14-3-3σ/ERα stabilizer-1 (Compound 181) is a covalent 14-3-3σ/ERα stabilizer. 14-3-3σ/ERα stabilizer-1 can be used for research of molecular glues[1].
Name 14-3-3σ/ERα stabilizer-1
Formula C25H35Cl2N3O3
Molar Mass 496.47
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Konstantinidou M, et al. Structure-Based Optimization of Covalent, Small-Molecule Stabilizers of the 14-3-3σ/ERα Protein-Protein Interaction from Nonselective Fragments. J Am Chem Soc. 2023 Sep 20;145(37):20328-20343.