| Bioactivity | Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated from Psoralea corylifolia (L.), is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for the serotonin transporter (SERT) (IC50=312.02 μM). 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson's disease, depression, and cocaine addiction[1]. |
| Target | IC50: 0.58 μM (dopamine transporter)IC50: 0.69 μM (norepinephrine transporter) |
| Name | 13-Hydroxyisobakuchiol |
| CAS | 178765-49-6 |
| Formula | C18H24O2 |
| Molar Mass | 272.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gang Zhao, et al. Bakuchiol analogs inhibit monoamine transporters and regulate monoaminergic functions. Biochem Pharmacol. 2008 May 1;75(9):1835-47. |
13-Hydroxyisobakuchiol
CAS: 178765-49-6 F: C18H24O2 W: 272.38
Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated from Psoralea corylifolia(L
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.