| Bioactivity | 12-OAHSA is a component of olive oil. 12-OAHSA has oral activity, and improves glucose homeostasis in insulin resistant obese mice[1]. |
| Invitro | 12-OAHSA (25 μM，24 小时) 抑制 Raw 264.7 巨噬细胞中 LPS 诱导的 IL-1b、IL-6、Nos2 和 Tnf-α[1]。12-OAHSA (25 μM，6 小时)可降低 Raw 264.7 巨噬细胞中 IKKβ 磷酸化并增加 p65 磷酸化[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> 12-OAHSA 相关抗体: |
| In Vivo | 12-OAHSA (30 mg/kg，口服，持续 10 天) 可抑制 HFD 诱导的肥胖 C57BL/6 小鼠中肥胖诱导的胰岛素抵抗[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 101901-73-9 |
| Formula | C36H68O4 |
| Molar Mass | 564.92 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Moyo KM, et al. 12-OAHSA is a component of olive oil and mitigates obesity-induced inflammation. J Nutr Biochem. 2022 Dec;110:109127. |