| Bioactivity | 11β-HSD1-IN-7 (compound c10a) is a 11β‑HSD1 inhibitor with an IC50 value of 1.9 μM for human 11β‑HSD1. 11β-HSD1-IN-7 can be used for the research of diabetes and cognitive decline[1]. | ||||||||||||
| Target | IC50: 1.9 μM (human 11β‑HSD1) | ||||||||||||
| Invitro | 11β-HSD1-IN-7 (0-50 μM) inhibits human and rat 11β‑HSD1 with IC50 values of 1.9 μM and ＞50 μM, respectively[1]. | ||||||||||||
| Name | 11β-HSD1-IN-7 | ||||||||||||
| CAS | 728-86-9 | ||||||||||||
| Formula | C14H9F3O | ||||||||||||
| Molar Mass | 250.22 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Naredo-Gonzalez G, et al. Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19F-Magnetic Resonance Spectroscopy. Sci Rep. 2022 Sep 29;12(1):16268. |