| Bioactivity | 11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4. It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea. |
| CAS | 79768-40-4 |
| Formula | C₂₅H₄₀N₂O₆S |
| Molar Mass | 496.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Krell, et al. Contraction of isolated airway smooth muscle by synthetic leukotrienes C4 and D4. Prostaglandins 22(3), 387-409 (1981). |
11-trans Leukotriene D4
CAS: 79768-40-4 F: C₂₅H₄₀N₂O₆S W: 496.66
11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent
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